The future of US vaccine policy is uncertain as the country moves beyond the emergency phase of the COVID-19 pandemic. The article explores the complex transition from government-led mandates and centralized distribution to a more fragmented, market-driven system. Key questions remain about who will pay for vaccines, how often boosters will be needed, and how to ensure equitable access. Public health officials face the challenge of maintaining high vaccination rates without the emergency framework that previously guided efforts. The path forward involves navigating political divisions, evolving science, and a healthcare system ill-prepared for ongoing population-wide immunization campaigns. Read the full article at: https://www.wired.com/story/no-one-knows-where-us-vaccine-policy-goes-next/