A new study reveals that a major reason many promising cancer drugs fail in human clinical trials is due to fundamental differences in how tumors behave in laboratory mice versus humans. Researchers found that the tumor microenvironment—the complex ecosystem of blood vessels, immune cells, and connective tissue surrounding cancer cells—differs significantly between species. These differences …

A new study suggests that a widely available dietary nutrient may significantly enhance the effectiveness of certain cancer therapies. The research, conducted on cell cultures and animal models, found that this nutrient helps overcome treatment resistance by making cancer cells more vulnerable. This approach could potentially improve outcomes for patients without adding severe side effects, …

A new study reveals the mechanism by which aggressive triple-negative breast cancer (TNBC) evades the body's immune defenses. Researchers discovered that TNBC tumors produce high levels of a protein called TSPAN6, which activates a specific signaling pathway within tumor cells. This pathway, in turn, causes the tumor cells to release a chemical signal that deactivates …

A new study has identified a potential method to control the Epstein-Barr virus (EBV), a common herpesvirus carried by an estimated 95% of the global adult population. While often asymptomatic, EBV is linked to several serious conditions, including multiple sclerosis and certain cancers. Researchers discovered that a specific viral protein, essential for EBV's ability to …